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What is DXM? Order dextromethorphan
Dextromethorphan (DXM or DM) is a drug of the morphinan class with sedative, dissociative, and stimulant properties
(at higher doses). When taken far above its standard medical dosage, becomes a powerful dissociative drug with
psychedelic properties. It is one of the active ingredients in many common over-the-counter (OTC) cold and cough
Dextromethorphan is also used in other areas of medicine, ranging from pain relief (as either the primary analgesic, or
an opioid potentiator) over psychological applications to the treatment of addiction. In its pure form,
dextromethorphan occurs as a white powder, although it is most commonly consumed or sold in syrup, tablet, spray,
and lozenge forms. In its pure form, dextromethorphan occurs as a white powder
-Pure DXM HCl; There is another form of DXM HCl (Hydrochloride) which is much cleaner than the HBr that is in
most syrups and gel caps. The HCl form of DXM is the holy grail as it can be taken in a small capsule at doses
around 500 mg avoiding all the negative effects of the HBr (Hydrobromide).
-Gel Caps; DXM Gelcaps such as Robitussin Gelcaps or other no-name-brand products containing only DXM
encased in a gelcap are often the preferred source for DXM users
-Lozenges; There are also sore-throat and cough medications containing DXM which exist in the form of a hard-
candy like lozenge. These sometimes contain only DXM, however most brands of DXM lozenges also contain
analgesics such as acetaminophen or benzocaine.
-Syrup; This Cough syrup is the most common source for DXM users. While there are many brand name and no-
name syrups which only contain DXM as an active ingredient there are many active and "inactive" ingredients
commonly found in cough syrups which can cause negative effects ranging in severity.
-Delsym; Delsym is brand with many formulations which contain Dextromethorphan Polistrex.
Dissociative; Psychedelic; Cough Suppressant
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Generic structure of morphinan molecule.
Dextromorphan is a dextrorotatory molecule of the morphinan class. It contains a phenanthrene core structure with one
aromatic ring (benzene) bound to two saturated rings (cyclohexane). Additionally, it contains a saturated piperidine ring
attached to R9 and R13 of the core structure. DXM is substituted at RN with a methyl group and at R3 with a methoxy group.
Many DXM-containing products (such as Coricidin Cough and Cold) also contain other active ingredients which can be
dangerous or fatal in high doses.
DXM is also used recreationally. When exceeding approved dosages, dextromethorphan acts as a dissociative anesthetic. Its
mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1
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